AYURVEDIC MEDICINAL PLANTS AND THEIR NEUROPROTECTIVE POTENTIAL IN ALZHEIMER'S DISEASE

Bargale Sushant Sukumar; Shashirekha H K; Neha Gadgil; Akshar Kulkarni; Harshal Tare

doi:10.21271/ZJPAS.37.3.1

Authors

Bargale Sushant Sukumar Department of Swasthavritta and Yoga, Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka, India.
Shashirekha H K Department of Samhita Sanskrit, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Neha Gadgil Department of Kriya Sharir, Sri Lal Bahadur Shastri Smarak Rajakiya Ayurvedic Mahavidyalaya, Handia, Prayagraj, Uttar Pradesh, India.
Akshar Kulkarni Department of Samhita Siddhanta, Parul Institute of Ayurved, Parul University, Vadodara, Gujarat, India
Harshal Tare Department of Pharmacognosy, SGMSPM’s Sharadchandra Pawar College of Pharmacy, Otur, Affiliated to Savitribai Phule Pune University, Pune, Maharashtra, India.

DOI:

https://doi.org/10.21271/ZJPAS.37.3.1

Keywords:

Ayurveda, AD, neuroprotection, medicinal plants, holistic medicine, integrative therapy, personalized medicine, clinical trials, neurodegenerative diseases

Abstract

Alzheimer's Disease (AD) poses a substantial universal health challenge with limited effective treatment options. Ayurvedic medicinal herbs are being evaluated as prospective candidates for neuroprotection due to their diverse array of bioactive compounds and comprehensive therapeutic principles. This review compiles the latest information on Ayurvedic herbs. It examines their mechanisms of action, clinical effectiveness, safety profiles, and regulatory issues in the management of AD. Key findings highlight their potential to mitigate neuroinflammation, oxidative stress, and cognitive decline, offering insights into integrative approaches that synergize traditional wisdom with modern pharmacotherapy. Future research directions underscore the need for mechanistic studies, large-scale clinical trials, and personalized medicine strategies to optimize therapeutic outcomes in AD.

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