Prevalence of infections with antibiotic-resistant Acinetobacter baumannii in different clinical samples from hospitals in Erbil

Sakar B. Smai; Aryan R. Ganjo

doi:10.21271/ZJPAS.32.3.11

Authors

Sakar B. Smai Par Private hospital, Erbil, Kurdistan Region, Iraq
Aryan R. Ganjo Department of Pharmacognosy, College of Pharmacy, Hawler Medical University, Erbil, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.21271/ZJPAS.32.3.11

Keywords:

Acinetobacter baumannii, Carbapenems, Multi-drug resistance, Nosocomial infections

Abstract

Drug-resistant Acinetobacter baumannii is one of the important pathogen causing nosocomial infections. This pathogen is becoming resistant to a large group of antimicrobial agents, leading to a high rate of mortality and morbidity. The aim of the study was to determine the prevalence of Acinetobacter baumannii isolates from different clinical samples and analyze its antibiotic susceptibility profiles, and pathogenic perspective. During the period of study from November 2016 to December 2017, different clinical specimens including (urine, wound swab, burn, sputum and blood) obtained from patients hospitalized in Par private hospital and Rizgari teaching hospital in Erbil city. Conventional microbiological methods were used for identification of A. baumannii. Antibiotic susceptibility testing was performed by the method commended by the Clinical Laboratory and Standards Institute (CLSI). A. baumannii nosocomial infection was increasing especially in patients with risk factors, the current study showed that sputum isolates are the most frequently encountered 20 (51.3%) followed by others. The prevalence of A. baumannii according to person ̕s gender among the 39 positive growth 25(17.1%) were from males and 14(12.3%) from females. The study revealed that there was an increase in antimicrobial resistance, most of the isolates even non susceptible to carbapenems with the exception of colistin that had an effective rule in comparison with the others. The study showed that the incidence of multi-drug resistance A. baumannii was high and the rate of resistance in A. baumannii to carbapenems was rising. Most isolates of A. baumannii were multi-resistance against antibiotics.

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