Synthesis , Antibacterial Activity of Sm(III) Complex With L-phenylalanine

Abstract

      Samarium–amino acid complex in aqueous solution was synthesized in formula:[Sm(phen)₃].H₂O, by reaction of  L-phenylalanine (phen) with samarium chloride hexahydrate (SmCl₃.6H₂O) in (1:3) M:L mole ratio . The structure was confirmed by FT-IR, UV-Vis. spectroscopy and ¹H-NMR ¹³C-NMR techniques, and characterized by elemental analysis and molar conductivity  measurements, molar conductance values in DMSO indicate the non-electrolyte behaver of [Sm(phen)₃].H₂O complex with mole ratio (1:3). The ligand (L-phenylalanine) behaves as bidentate. Coordination sites is oxygen atom of carboxylate group –COOH after deprotonation and nitrogen atom from amino group –NH₂ the obtained data indicated that the complex has octahedral geometry.The samarium complex seem to be more active than L-phenylalanine ligand in terms of antimicrobial activity , these results show that Sm(III) complex has an antibacterial effect can be apply as antimicrobial active species.

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